Detalhe da pesquisa
1.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 184(18): 4651-4668.e25, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450028
2.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 187(6): 1565-1566, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490183
3.
Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients.
Int J Mol Sci
; 21(15)2020 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32707880
4.
High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II.
Int J Mol Sci
; 21(15)2020 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32751752
5.
Heel Pain Management in Haglund's Deformity Targeting Sural Nerve Branches under Ultrasound Guidance: Case Report.
J Orthop Case Rep
; 14(2): 12-17, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38420222
6.
Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia.
bioRxiv
; 2024 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405775
7.
Knowledge and Awareness About Diabetes Mellitus Among Urban and Rural Population Attending a Tertiary Care Hospital in Haryana.
Cureus
; 15(4): e38359, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37266052
8.
Ondansetron-induced QT prolongation among various age groups: a systematic review and meta-analysis.
Egypt Heart J
; 75(1): 56, 2023 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37395900
9.
The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport.
Neurobiol Dis
; 47(1): 126-34, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22516235
10.
Ca(2+)-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion.
Nat Struct Mol Biol
; 13(4): 323-30, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16565726
11.
Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome.
JCI Insight
; 6(19)2021 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34622797
12.
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.
Sci Transl Med
; 12(545)2020 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461331
13.
Atomic force microscope spectroscopy reveals a hemifusion intermediate during soluble N-ethylmaleimide-sensitive factor-attachment protein receptors-mediated membrane fusion.
Biophys J
; 94(2): 648-55, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17872963
14.
Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor.
Mol Cell Biol
; 25(19): 8693-702, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16166648
15.
Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion.
Mol Biol Cell
; 16(10): 4755-64, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16093350
16.
Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor.
Br J Pharmacol
; 144(6): 761-71, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15778699
17.
Synaptotagmin IV: a multifunctional regulator of peptidergic nerve terminals.
Nat Neurosci
; 12(2): 163-71, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19136969
18.
Pulling force generated by interacting SNAREs facilitates membrane hemifusion.
Integr Biol (Camb)
; 1(4): 301-10, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20023730
19.
Analysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoforms.
J Biol Chem
; 283(31): 21799-807, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18508778
20.
A profile of substance abusers using the emergency services in a tertiary care hospital in Sikkim.
Indian J Psychiatry
; 48(4): 243-7, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20703344